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Advantech has all the USB isolators you need to provide RS-232 connectivity and protection against harmful noise, ground loops, surges, and spikes.
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Advantech BB-UH401 BB-UH401

Advantech USB to USB 1- Port Isolator

ESP Price: $143.00
Advantech BB-UH401-2KV BB-UH401-2KV

Advantech USB TO USB 1 PORT ISOLATOR - 2KV

ESP Price: $123.00
Advantech BB-UHR401 BB-UHR401

Advantech USB TO USB 1 PORT ISOLATOR - 4KV, RUGGED

ESP Price: $202.00
Advantech BB-UHR402 BB-UHR402

Advantech USB TO USB 2 PORT ISOLATOR / HUB - 4KV, RUGGED

ESP Price: $213.20